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Ctive, with favorable clinical response rates (i.e., cure rates) of 80 at the TOC visit, 150 subjects per treatment group were required to ensure with 90 power that the lower bound of a two-sided 95 confidence interval (CI) for the true difference in efficacy (tigecycline minus comparator) corrected for continuity did not exceed -15 . The noninferiority of tigecycline compared with comparator w

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